Oxidative stress and risk factors for cerebrovascular diseases

Abstract

Oxidative stress refers to the pathological process of cell oxidative damage that caused by increased reactive oxygen species (ROS) aggregation in vivo, due to the excessive generation of ROS and/or decreased anti-oxidant ability, resulting in imbalance between ROS producing and scavenging mechanism. Oxidative stress, which is closely related with cerebrovascular diseases, is involved in the pathological process of many diseases. Several cerebrovascular disease risk factors, such as smoking, blood glucose fluctuation, hyperlipemia, hypertension and hyperhomocysteinemia, can cause the increasing of ROS.

doi: 10.3969/j.issn.1672-6731.2014.10.016