Predictive value of initial intracranial pressure for the prognosis of patients with traumatic brain injury

Abstract

This paper aims to investigate the predictive value of initial intracranial pressure (ICP) for the prognosis of patients with traumatic brain injury (TBI). A prospective observational study was conducted in 118 TBI patients with ICP monitoring. The initial ICP [receiver operating characteristic (ROC) area = 0.725; 95%CI: 0.635-0.815] was similar to admission Glasgow Coma Scale (GCS; ROC area = 0.716; 95% CI: 0.616-0.816) or Marshall classification (ROC area = 0.690; 95% CI: 0.593-0.787) in predicting the prognosis of TBI patients. A Logistic regression analysis showed that initial ICP was associated with poor prognosis in TBI patients (OR = 0.943, 95%CI: 0.899-0.988; P = 0.014). The initial ICP in TBI patients could be used as an independent predictor of TBI patients' outcomes.

doi: 10.3969/j.issn.1672-6731.2014.08.015