Research progress of functional brain ⁃ neuroimaging technology in Parkinson's disease with gait disorder

Zhi⁃zhong ZHU, Yang YU, Ning⁃bo YU, Jia⁃ling WU

Abstract


Gait disorder appears in the whole process of Parkinson's disease (PD), which causes disability and serious affects in PD patients. The mechanism of gait disorder in PD is still unclear. Functional brain ⁃ neuroimaging can be used to analyse the characteristics and rules of brain functional activity related to gait disorder in PD, and has important clinical significance in revealing the neural physiopathologia mechanism of gait disorder, guiding the treatment and evaluating the curative effect. This paper briefly summarizes the research progress of fMRI and functional near⁃infrared spectroscopy (fNIRS) in gait disorder of PD, to provide reference for future research.

DOI：10.3969/j.issn.1672⁃6731.2020.12.013

Keywords


Parkinson disease; Gait disorder, neurologic; Magnetic resonance imaging; Spectroscopy, near⁃infrared; Review

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